2000
The Center for Genetic Engineering and Biotechnology begins to use plants to produce recombinant biopharmaceuticals. Hep-1 antibody production begins in plants. Hepatitis B vaccine antigen is purified using the “plantibody”. Cuba achieves that cases of children under five years of age with hepatitis B are not reported, thanks to the application of the Heberbiovac-HB® vaccine, against hepatitis B and its consequences, registered in more than 35 countries.