Historia del CIGB/ GEBC History

Historia del CIGB/ GEBC History
1981
May 28

Primera producci贸n del interfer贸n / First production of interferon

Se logra obtener el primer interfer贸n cubano y se comienza el uso en el tratamiento de paciente con Dengue hemorr谩gico y conjuntivitis hemorr谩gica. The first Cuban interferon is obtained and the use in the treatment of patients with hemorrhagic dengue and hemorrhagic conjunctivitis is started.
1982
January 21

Inauguraci贸n del CIB / Inauguration of the CIB

Inauguraci贸n del Centro de Investigaciones Biol贸gicas (CIB) por Fidel Castro y el profesor Kari Cantell. Inauguration of the Center for Biological Research (CIB) by Fidel Castro and professor Kari Cantell.
1984
January 9

Interfer贸n / Interferon

Se registra el Interfer贸n leucocitario humano. Human leukocyte interferon is registered.
1985
January 6

Primeros anticuerpos y planta transg茅nica / First antibodies and transgenic plant

Se producen los primeros anticuerpos monoclonales cubanos (IFN2.1 e IOR-T1) y se聽obtiene la primera planta transg茅nica en Cuba. The first Cuban monoclonal antibodies (IFN2.1 and IOR-T1) are produced and is obtained the first transgenic plant in Cuba.
1986
July 1

Inauguraci贸n del CIGB / Inauguration of CIGB

Inauguraci贸n del Centro de Ingenier铆a Gen茅tica y Biotecnolog铆a de La Habana por Fidel Castro. Inauguration of the Genetic Engineering and Biotechnology Center in Havana by Fidel Castro. “… el centro es grande, pero yo espero que sean grandes tambi茅n lso resultados cient铆ficos que se obtengan…”
1987
February 6

Expresi贸n del HbsAg en c茅lulas CHO / Expression of HbsAg in CHO cells

Expresi贸n del HbsAg en c茅lulas CHO, primera prote铆na recombinante que se expresa en Cuba en c茅lulas de mam铆feros. Expression of HbsAg in CHO cells, the first recombinant protein expressed in Cuba in mammalian cells.
November 13

IFN alfa2 humano / human IFN alpha 2

Se realiz贸 la secuenciaci贸n del primer gen completo en el CIGB ( IFN alfa2 humano). the first complete gene sequencing was performed at the CIGB (human IFN alpha 2).
1989
September 6

Apoyo cubano en la antigua URSS / Cuban support in the former USSR

Apoyo de Cuba con la aplicacion del EGF crema en la cat谩strofe ocurrida en Bashkiria,URSS. Support of Cuba with the application of cream EGF in the disaster in Bashkiria, USSR.
October 9

CIGB Camag蠇ey / GEBC Camag蠇ey

Se inaugura el Centro de Ingenier铆a Gen茅tica y Biotecnolog铆a de Camag蠇ey. Is inaugurated the Genetic Engineering and Biotechnology聽Center of Camag蠇ey.
1990
January 9

CIGB Sancti Spiritus / GEBC Sancti Spiritus

Inauguraci贸n del CIGB de Sancti Spiritus. Is inaugurated the Genetic Engineering and Biotechnology聽Center of Sancti Spiritus.
June 14

Vacuna contra la Hepatitis B / Hepatitis B Vaccine

Comienza la producci贸n de la vacuna contra la Hepatitis B y posteriormente, en 2001, es certificada por la OMS. Production of the Hepatitis B vaccine begins, and in 2001, it is certified by WHO.
1991
April 9

Heber Biotec / Heber Biotec

Se crea la empresa comercializadora HEBER BIOTEC. HEBER BIOTEC bussines聽company is created.
1992
September 15

VIH / HIV

Se demostr贸 que el uso prolongado del FT y del IFN retrasan la progresi贸n de la enfermedad en individuos con VIH. Prolonged use of FT and IFN was shown to delay the progression of the disease in HIV-positive individuals.
1993
February 5

infarto del miocardio / myocardial infarction

Se introduce en el pa铆s el tratamiento trombolitico con estreptoquinasa recombinante (Heberkinasa) en el infarto del miocardio. Thrombolytic treatment with recombinant streptokinase (Heberkinasa) is introduced in the country in myocardial infarction.
September 2

Vacuna GAVAC / Vaccine GAVAC

Se produce el ant铆geno Bm86 para la vacuna contra la garrapata en el ganado. Se registra en 1994 en Colombia y Brasil. Bm86 antigen is produced for the tick vaccine in cattle. It is registered in 1994 in Colombia and Brazil.
1998
August 18

Cuba- Ir谩n / Cuba- Iran

Comienza transferencia tecnol贸gica a聽Ir谩n. Technological transfer to Iran begins.
2000
September 9

Protegidos los cubanos / Protected the Cuban people

Protegida la poblaci贸n cubana menor de 20 a帽os contra la Hepatitis B. Protected the Cuban people under 20 years against Hepatitis B.
2005
May 1

Vacuna Tetravalente / Vaccine Tetravalent

Introducci贸n de vacuna Trivac-HB (tetravalente) en el Programa Nacional de Inmunizaciones. La primera de su tipo en Latinoam茅rica. Introduction of Trivac-HB vaccine (tetravalent) in the National Immunization Program. The first of its kind in Latin America.
May 6

Acuabio 1 / Acuabio 1

Obtenci贸n de Patente y registro de Acuabio 1. Patenting and registration of Acuabio 1.
2007
June 30

Heberprot-P / Heberprot-P

Se comienza a utilizar el medicamento Heberprot-P para las 煤lceras del pie diab茅tico. Desde su creaci贸n a la actualidad ha curado a miles de pacientes. Es patentado en varios pa铆ses. Da comienzo tambi茅n el Programa de Atenci贸n Integral al Paciente con 脷lceras del Pie Diab茅tico. The medicine Heberprot-P is used for diabetic foot ulcers. From its creation to today it has cured thousands of patients. It is patented in several countries. Also the Program of Integral Care to the Patient with Diabetic Foot Ulcers begins.
2010
July 12

Vacuna Pentavalente / Vaccine Pentavalent

Se obtuvo el registro en 2010 de una nueva vacuna pentavalente l铆quida en un solo vial que protege a la vez contra cinco enfermedades: Difteria, Tosferina, T茅tanos, Hepatitis B e infecciones por Haemophilus influenzae Tipo B. A new pentavalent liquid vaccine was registered in 2010 in a single vial that protects at the same time against five diseases: Diphtheria, Tosferina, Tetanus, Hepatitis B and Haemophilus influenzae Type B infections.
2012
August 16

Certificaci贸n ISO / Certification ISO

El CIGB cuenta con la Certificaci贸n NC-ISO 9001:2008 con alcance a toda la instituci贸n excepto a las investigaciones agropecuarias y las filiales de Sancti Spir铆tus y Camag蠇ey. The CIGB聽has the Certification NC-ISO 9001: 2008 with scope to all the institution except the agricultural investigations and the subsidiaries of Sancti Spir铆tus and Camag蠇ey.
2014
January 18

Empresa Mixta Lukang-Heber / Lukang-Heber Joint Company

Constituci贸n de la Empresa Mixta Lukang-Heber entre Heber Biotec y Lukang, China, para productos biotecnol贸gicos agropecuarios. Constitution of the Lukang-Heber Joint Company between Heber Biotec and Lukang, China, for agricultural biotechnological products.
2015
March 9

Certificado de Buenas Pr谩cticas / Good Manufacturing Practices certificate

Se obtuvo el certificado de Buenas Pr谩cticas de Fabricaci贸n del sistema BIOCEN – SAOKIM (Vietnam) para la producci贸n de supositorio de estreptoquinasa. The Good Manufacturing Practices certificate of the BIOCEN – SAOKIM system (Vietnam) was obtained for the production of streptokinase suppository.
April 7

Medicamentos Esenciales para la Vida / Essential Drugs for Life

Se logr贸 la inclusi贸n del Heberprot-P en el Listado de Medicamentos Esenciales para la Vida de la Federaci贸n Rusa. Heberprot-P was included in the List of Essential Drugs for Life of the Russian Federation.
October 24

Cl铆nica en la Rep煤blica Argelina / Clinic in the Republic of Algeria

Abren en la Rep煤blica Argelina Democr谩tica y Popular cl铆nica para el tratamiento de la 煤lcera del pie diab茅tico con Heberprot-P. Is opens in the Democratic Republic of Algeria a clinic for the treatment of diabetic foot ulcer with Heberprot-P.
2016
March 2

Cuba- Rusia / Cuba-Russia

Cuba y Rusia suscriben cuatro acuerdos de cooperaci贸n biom茅dica. Cuba and Russia make four biomedical cooperation agreements.
July 1

30 Aniversario del CIGB/ 30th CIGB Anniversary

El centro de Ingenier铆a Gen茅tica y Biotecnolog铆a cumple 30 a帽os desde su fundaci贸n, en 1986, por el Comandante en Jefe Fidel Castro. The Genetic Engineering and Biotechnology Center celebrates 30 years since its founding in 1986 by Fidel Castro.
August 4

Registro Sanitario HeberFeron/Health Registry HeberFeron

Aprueban registro sanitario en Cuba de producto cubano HeberFeron para el c谩ncer de piel/Cuba sanitary registry of Cuban product HeberFeron approved for skin cancer
2017
January 6

Ensayos Cl铆nicos en EE.UU de vacuna contra el c谩ncer/US Clinical Trials of Cancer Vaccine

Comenzaron ensayos cl铆nicos en EEUU de vacuna cubana contra el c谩ncer/Clinical trials began in the US of Cuban vaccine against cancer
June 30

10mo Aniversario Heberprot-P/10th Anniversary Heberprot-P

Cumple 10 a帽os de aplicaci贸n en Cuba del producto Heberprot-P para las ulceras de pie diabetico/It has been 10 years of application in Cuba of the Heberprot-P product for diabetic foot ulcers
November 29

Registro en Cuba de PORVAC/Registration in Cuba of PORVAC

Concedido el Registro en Cuba de PORVAC (Vacuna contra el virus de la Peste Porcina Cl谩sica)/The Registry in Cuba of PORVAC (Vaccine against the Classical Swine Fever Virus) was granted
2018
March 20

EE.UU-Cuba, uso de Heberprot-P/USA-Cuba, use of Heberprot-P

Empresas estadounidenses y cubanas llegaron a un acuerdo sobre Heberprot-p/US and Cuban companies reached an agreement on Heberprot-p
April 25

Heberprot-P, comienza sus pasos hacia M茅xico/Heberprot-P, begins its steps towards Mexico

Registra M茅xico medicamento cubano para pie diab茅tico/Register Mexico Cuban medication for diabetic foot
June 3

Premio de Invenci贸n a producto cubano/Invention Award for Cuban product

Otorgan Premio de Invenci贸n a novedoso producto m茅dico cubano/Award of Invention for novel Cuban medical product